If you’ve been researching wrinkle relaxers, you’ve probably come across names like Botox, Jeuveau, Dysport, Xeomin, Daxxify, and Letybo. With so many options, it’s easy to feel overwhelmed.
At Retro Health & Aesthetics, we currently offer Botox and Jeuveau, and we’re excited to be adding Dysport soon. This post is my honest breakdown of what makes each one different — and how we think about finding the right fit for you.
The good news? All of these products work in a very similar way. The biggest difference is choosing the one that’s the best fit for your face, your goals, and your history.
Neurotoxins are injectable medications that temporarily relax the muscles that cause wrinkles from facial expressions. By blocking the nerve signals that trigger muscle contractions, they allow the overlying skin to smooth out — reducing dynamic wrinkles that form from repeated movement.
They help soften:
Most treatments last about 3–4 months, although everyone is a little different. Many patients notice that with regular treatments, their results last longer over time as muscle activity diminishes.
The key differences between products come down to molecular formulation, onset time, spread, duration, and price point. Here’s how each one stacks up.
Jeuveau (prabotulinumtoxinA-xvfs) is our primary neurotoxin at Retro Health, and for good reason.
Jeuveau was FDA-approved in 2019 specifically for the treatment of glabellar lines (the “11s” between the brows). It’s the only neurotoxin developed entirely in the modern era, using a highly purified formulation and a newer manufacturing process.
We love it because:
Although Jeuveau is FDA-approved specifically for the “11s,” it’s commonly and safely used in many other treatment areas — forehead lines, crow’s feet, lip flips, brow lifts — as part of standard medical practice. This is true of all neurotoxins.
We’re excited to be adding Dysport (abobotulinumtoxinA) to our offerings, and I’m genuinely enthusiastic about what it brings to the table for certain patients.
Dysport uses a different formulation with a wider diffusion pattern than Jeuveau or Botox. That spread can be a disadvantage in small, precise areas — but it’s actually an advantage in larger treatment zones like the forehead, where you want more even distribution with fewer injection points.
Many patients like Dysport because:
One important thing to know: Dysport uses a different unit system than Botox and Jeuveau. Roughly 2.5–3 units of Dysport is equivalent to 1 unit of Botox or Jeuveau. So don’t compare treatments by unit count alone — a higher number doesn’t mean more product, it’s just a different measurement system.
Adding Dysport gives us more flexibility to match the right product to each patient’s anatomy, goals, and response history. Not brand loyalty — clinical fit.
Botox (onabotulinumtoxinA) is the most well-known wrinkle relaxer and has been safely used for decades. It’s the product that put neurotoxins on the map, and it remains an excellent option — especially for patients who have an established history with it.
Many patients choose Botox because:
If you’ve always done well with Botox, we’re happy to continue using it. A patient who knows exactly how they respond to a product has real information — and we respect that.
The truth is, there isn’t one “best” neurotoxin for everyone.
Botox, Jeuveau, and Dysport are all FDA-approved, safe when administered by a trained medical professional, effective at reducing dynamic wrinkles, and capable of producing beautiful, natural-looking results.
What I tell patients who ask me to compare: the biggest factor in your outcome isn’t the brand — it’s the skill and experience of your injector, and choosing the right treatment plan for your face.
We don’t believe one product is right for everyone. Instead, we recommend the neurotoxin that best matches your:
Our goal is always the same: natural-looking results, conservative dosing, personalized treatment, and a follow-up to make sure you love what you see. We want you to look refreshed and confident — not frozen.
You don’t have to figure it out on your own. During your consultation, we’ll evaluate your facial muscles, discuss your goals, and recommend the option that’s the best fit for you.
I’d love to help you find it.
Maggie Howard is an aesthetic injector at Retro Health & Aesthetics in Worthington, Ohio. She specializes in neurotoxin treatments, dermal fillers, and non-surgical facial aesthetics.
